p300 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer:  Bethyl Laboratories, Inc A300358A

Catalog No. 50-155-7448

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.

Specifications

• Antigen: p300
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EP300
• Format: liquid
• Gene Symbols: EP300
• Immunogen: Between 950 and 1000
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human

• Applications: ChIP-sequencing, Immunohistochemistry, Immunoprecipitation, Western Blot
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q09472
• Gene Alias: CREBBP/EP300 inhibitory protein 1, Cyclic AMP responsive enhancer binding protein, EP300: E1A binding protein p300, RB and P300 binding protein EID 1,
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μl
• Storage Requirements: 4° C
• Primary or Secondary: Primary
• Gene ID (Entrez): 2033