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p33ING1Goat anti-Human, Polyclonal, Rockland™
SDP

Catalog No. 501991554
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100 μg
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Catalog No. Quantity
50-199-1554 100 μg
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Catalog No. 50-199-1554 Supplier Rockland Immunochemicals Supplier No. 600101282
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Description

Goat Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Reactivity occurs against human p33 ING1 protein and is 100% homologous to all splice variants for ING1. Cross reactivity with p33 ING1 protein from mouse and rat sources is expected based on high homology (one amino acid change in sequence) by BLAST. Reactivity with p33 ING1 proteins from other sources is not known.

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

Antigen p33ING1
Applications ELISA, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene ING1
Gene Accession No. Q9UK53
Gene Alias 2610028J21Rik; AA407184; AI875420; growth inhibitor ING1; growth inhibitory protein ING1; ING1; inhibitor of growth family member 1; inhibitor of growth family, member 1; Inhibitor of growth protein 1; mING1h; p24ING1c; p33; p33ING; p33ING1; p33ING1b; p33ING1c; p37Ing1b; p47; p47ING1a; tumor suppressor ING1
Gene Symbols ING1
Host Species Goat
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3621
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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