Invitrogen™ P3H3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106424

Catalog No. PIPA5106424

Description

Antibody detects endogenous levels of total P3H3.

The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.

Specifications

• Antigen: P3H3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: P3h3
• Gene Alias: BC016431; gene rich cluster, B; GRCB; HSU47926; leprecan-like 2; leprecan-like protein 2; LEPREL2; P3H3; procollagen-proline 3-dioxygenase; prolyl 3-hydroxylase 3; Protein B
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10536, 14789, 297595
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8CG70, Q8IVL6
• Gene Symbols: P3h3
• Immunogen: A synthesized peptide derived from human P3H3(Accession Q8IVL6), corresponding to amino acid residues D578-E628.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov