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p40 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA592205
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PIPA592205 100 μL
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Catalog No. PIPA592205 Supplier Thermo Scientific Supplier No. PA592205

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MKQLPVLEPG DKPRKATWYT LTVPGDSPCA RVGHSCSYLP PVGNAKRGKV FIVGGANPNR SFSDVHTMDL GKHQWDLDTC KGLLPRYEHA SFIPSCTPDR IWVFGGANQS GNRNCLQVLN PETRTWTTPE VTSPPPSPRT FHTSSAAIGN QLYVFGGGER GAQPVQDTKL HVFDANTLTW SQPETLGNPP SPRHGHVMVA AGTKLFIHGG LAGDRFYDDL HCIDISDMKW QKLNPTGAAP; Positive Samples: HeLa; Cellular Location: Cytoplasm, Endosome membrane

The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
TRUSTED_SUSTAINABILITY

Specifications

Antigen p40
Applications Western Blot
Classification Polyclonal
Concentration 3.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Rabepk
Gene Accession No. Q7Z6M1
Gene Alias 40 kDa Rab9 effector protein, 8430412M01Rik, 9530020d24rik, AV073337, bA65N13.1, C87311, p40, Rab9 effector p40, rab9 effector protein with kelch motifs, RAB9P40, RABEPK, RGD1310612
Gene Symbols Rabepk
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RAB9P40 (NP_0058242)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10244
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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