Invitrogen™ p47phox Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531169

Catalog No. PIPA531169

Description

Recommended positive controls: Raji, mouse spleen. Predicted reactivity: Mouse (84%), Rat (82%), Pig (84%), Rabbit (86%), Bovine (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

p47phox (NCF1) is required, along with NCF2 and membrane bound cytochrome b558, for activation of the latent NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in the gene can result in granulomatous disease.

Specifications

• Antigen: p47phox
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ncf1
• Gene Alias: 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NADPH oxidase subunit (47 kD); NADPH oxidase subunit (47kDa); Ncf1; NCF-1; NCF1A; NCF-47K; neutrop; neutrophil cytosol factor 1; neutrophil cytosolic factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); neutrophil NADPH oxidase factor 1; Nox organizer 2; NOXO2; nox-organizing protein 2; P47 phox; p47>phox>; p47phox; p47-phox; phagocyte oxidase 47 kDa; SH3 and PX domain-containing protein 1A; SH3PXD1A
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17969, 653361
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P14598, Q09014
• Gene Symbols: Ncf1
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 228 of Human NCF1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG