Invitrogen™ p47phox Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA19073

Catalog No. 01-674-657

Description

This antibody is predicted to react with bovine, mouse, porcine, rabbit and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 20,000.

p47phox (NCF1) is required, along with NCF2 and membrane bound cytochrome b558, for activation of the latent NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in the gene can result in granulomatous disease.

Specifications

• Antigen: p47phox
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ncf1
• Gene Alias: 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NADPH oxidase subunit (47 kD); NADPH oxidase subunit (47kDa); Ncf1; NCF-1; NCF1A; NCF-47K; neutrop; neutrophil cytosol factor 1; neutrophil cytosolic factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); neutrophil NADPH oxidase factor 1; Nox organizer 2; NOXO2; nox-organizing protein 2; P47 phox; p47>phox>; p47phox; p47-phox; phagocyte oxidase 47 kDa; SH3 and PX domain-containing protein 1A; SH3PXD1A
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 100134857, 17969, 653361
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P14598, Q09014
• Gene Symbols: Ncf1
• Immunogen: Synthetic peptide corresponding to the C terminus amino acids SESTKRKLASAV (aa 379-390).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Pig
• Product Type: Antibody
• Isotype: IgG