Invitrogen™ P4HA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552454

Catalog No. PIPA552454

Description

Immunogen sequence: FTSIGQMTDL IHTEKDLVTS LKDYIKAEED KLEQIKKWAE KLDRLTSTAT KDPEGFVGHP VNAFKLMKRL NTEWSELENL VLKDMSDGFI SNLTIQRQYF PNDEDQVGAA KALLRLQDTY NLDTDTISKG NLPGVKHKSF LTAEDC Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: P4HA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: P4HA1
• Gene Alias: 4-PH alpha-1; AL022634; collagen prolyl 4-hydroxylase alpha(I); C-P4Halpha(I); P4ha; P4ha1; PHalphaI; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1; prolyl 4-hydroxylase alpha subunit; prolyl 4-hydroxylase subunit alpha 1; prolyl 4-hydroxylase subunit alpha-1; prolyl 4-hydroxylase, alpha polypeptide I
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5033
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P13674
• Gene Symbols: P4HA1
• Immunogen: Recombinant protein corresponding to Human P4HA1. Recombinant protein control fragment (Product #RP-89690).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG