Invitrogen™ P4HA2 Monoclonal Antibody (CL0351)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524599

Catalog No. PIMA524599

Description

Immunogen sequence: LKEYILVEEA KLSKIKSWAN KMEALTSKSA ADAEGYLAHP VNAYKLVKRL NTDWPALEDL VLQDSAAGFI ANLSVQRQFF PTDEDEIGAA KALMRLQDTY RLDPGTISRG ELPGTKYQAM LSVDDCFGM Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 91%. Binds to an epitope located within the peptide sequence NTDWPALEDLVLQDS as determined by overlapping synthetic peptides.

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: P4HA2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O15460
• Gene Symbols: P4HA2
• Immunogen: Recombinant protein corresponding to Human P4HA2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CL0351
• Conjugate: Unconjugated
• Gene: P4HA2
• Gene Alias: 4-PH alpha 2; 4-PH alpha-2; 4PHalpha2; AA407196; C76437; collagen prolyl 4-hydroxylase alpha(II); C-P4Halpha(II); hypothetical protein LOC507327; P4HA2; P4hl; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2; prolyl 4-hydroxylase A; Prolyl 4-hydroxylase alpha IIa subunit; prolyl 4-hydroxylase subunit alpha 2; prolyl 4-hydroxylase subunit alpha-2; prolyl 4-hydroxylase, alpha polypeptide II; UNQ290/PRO330; zgc:91948
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 8974
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid