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p53 Ab-8 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS738P Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
7 mL
Form:
Concentrated
Prediluted
Concentration:
—
1mg/mL
200μg/mL
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Catalog No. Quantity Form Concentration
MS738P 1 mL Concentrated 200μg/mL
MS738P1ABX 100 μL Concentrated 1mg/mL
MS738P1 500 μL Concentrated 200μg/mL
MS738PABX 200 μL Concentrated 1mg/mL
MS738R1 1 mL Prediluted —
MS738R7 7 mL Prediluted —
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Description

Deliver accurate, reproducible results with the Epredia™ p53 Ab-8, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-7 + BP53-12

Isotype: IgG2b + IgG2a

Species Reactivity: Human. Others not known.

Epitope: aa 37-45 and aa 20-25

Immunogen: Recombinant human p53 protein

Molecular Weight: 53kDa

Positive Control: MDA-231, SKBR-3 cells or Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native and denatured)

Specifications

Antigen p53 Ab-8
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone DO-7 + BP53-12
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant human p53 protein
Quantity 1 mL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG2a, IgG2b
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