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p53 Ab-8 Mouse Monoclonal Antibody, Epredia™
Deliver accurate, reproducible results with the Epredia™ p53 Ab-8, Mouse Monoclonal Antibody.
Supplier: Epredia MS738P1ABX
Description
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Host Species: Mouse
Clone: DO-7 + BP53-12
Isotype: IgG2b + IgG2a
Species Reactivity: Human. Others not known.
Epitope: aa 37-45 and aa 20-25
Immunogen: Recombinant human p53 protein
Molecular Weight: 53kDa
Positive Control: MDA-231, SKBR-3 cells or Colon CA
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native and denatured)
Specifications
| p53 Ab-8 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 100 μL | |
| Cancer and Tumor Biology | |
| Human | |
| IgG2a, IgG2b |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| DO-7 + BP53-12 | |
| Unconjugated | |
| Recombinant human p53 protein | |
| IVD | |
| Primary | |
| Concentrated |
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