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  6. p57Kip2Ab-6 Mouse Monoclonal Antibody, Epredia™

p57Kip2Ab-6 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS1062RQ Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
7 mL
12 mL
Form:
Concentrated
Prediluted
Ready-to-Use
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Form Concentration
MS1062RQ 12 mL Ready-to-Use -
MS1062P0 100 μL Concentrated 200μg/mL
MS1062PABX 200 μL Concentrated 1mg/mL
MS1062P1 500 μL Concentrated 200μg/mL
MS1062P 1 mL Concentrated 200μg/mL
MS1062R7 7 mL Prediluted -
MS1062P1ABX 100 μL Concentrated 1mg/mL
MS1062R1 1 mL Prediluted -
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Catalog No. MS1062RQ Supplier Epredia Supplier No. MS1062RQ

Description

Deliver accurate, reproducible results with the Epredia™ p57Kip2 Ab-6, Mouse Monoclonal Antibody.

p57Kip2 (or CDKN1C) is a potent tight-binding inhibitor of several G1 cyclin complexes, and is a negative regulator of cell proliferation. The gene encoding human p57Kip2 is located on chromosome 11p15.5, a region implicated in both sporadic cancers, Wilm's tumor, and Beckwith-Wiedemann syndrome (BWS), a cancer syndrome, making it a tumor suppressor candidate. BWS is characterized by numerous growth abnormalities and an increased risk of childhood tumors. Several types of childhood tumors including Wilms' tumor, adrenocortical carcinoma and rhabdomyosarcoma display a specific loss of maternal 11p15 alleles, suggesting that genomic imprinting plays an important part. This region also contains two other imprinted genes, insulin-like growth factor II (IGF-II) and H19, both of which seem to be implicated in adrenal neoplasms.

Host Species: Mouse

Clone: 57P06; same as KP10

Isotype: IgG2b/κ

Species Reactivity: Human and Mouse. Others not known.

Epitope: Not determined

Immunogen: Recombinant human p57Kip2 protein

Molecular Weight: 57kDa

Positive Control: LS174T cells, Colon CA or placenta

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not suitable)
  • Immunoprecipitation (Native verified)

Specifications

Antigen p57superscriptKip2superscript Ab-6
Applications Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Clone 57P06; same as KP10
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant human p57superscriptKip2superscript protein
Quantity 12 mL
Regulatory Status IVD
Research Discipline Cell Cycle
Primary or Secondary Primary
Form Ready-to-Use
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