P5CS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-1741	Proteintech Group Inc 177191AP150UL	150 μL

Description

This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

Specifications

• Antigen: P5CS
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P54886, Q9Z110
• Gene ID (Entrez): 361755, 56454, 5832
• Immunogen: P5CS Fusion Protein Ag12100
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ALDH18A1

• Concentration: 0.2 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: ALDH18A1, GK, GPR, GSAS, P5CS, PYCS
• Gene Symbols: Aldh18a1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody