p600 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc IHC00640T

Catalog No. 50-157-2454

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Horse, Pig, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.

Specifications

• Antigen: p600
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q5T4S7
• Gene Symbols: UBR4
• Immunogen: Between 5133 and 5183
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunofluorescence, Immunohistochemistry
• Conjugate: Unconjugated
• Gene: UBR4
• Gene Alias: 600 kDa retinoblastoma protein-associated factor, KIAA0462, KIAA1307, N-recognin-4, p600, RBAF600, retinoblastoma-associated factor 600-like protein, retinoblastoma-associated factor of 600 kDa, zinc finger UBR1-type protein 1, zinc finger, UBR1 type 1, ZUBR1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23352
• Content And Storage: 4° C
• Form: Liquid