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p66alpha Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A302356AT

Encompass_Preferred

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Catalog No. 50-156-2399


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

Methylation of cytosine at CpG dinucleotides is a common feature of many higher eukaryotic genomes. Increasing evidence indicates that recruitement of histone deacetylase complexes by methyl-CpG-binding proteins (MeCP) is a major mechanism of methylated DNA silencing. P66, a zinc finger-containing protein is one of the components of the MeCP1 complex. P66 and p68, the two components of MeCP1 are different forms of the same zinc finger-containing protein and are conserved from C.elegans to humans. Homologs of p66 from different organisms revealed two highly conserved regions, CR1 and CR2. While CR1 is involved in the association of p66 with other MeCP1 components, CR2 plays an important role in targeting p66 and MBD3 to specific loci..
Specifications

Specifications

p66alpha
Polyclonal
TBS with 0.1% BSA and 0.09% sodium azide
Q86YP4
GATAD2A
Between 125 and 175
20 μL
Primary
Human
Antibody
IgG
Western Blot
Unconjugated
GATAD2A
1110066C11Rik, BC031407, C80248, MGC29315, MGC36975
Rabbit
Antigen affinity chromatography
RUO
54815
4° C
Liquid
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