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Tocris Bioscience™ PA 8

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Quantity:
10 mg
50 mg
Description
PA 8 is a PAC1 receptor antagonist. Inhibits PACAP-induced CREB phosphorylation in PAC1, but not VPAC1 or VPAC2, expressing cells. Also inhibits PACAP-induced increases in cAMP levels in vitro (IC50 = 2 nM) and PACAP-induced aversive responses and mechanical allodynia following intrathecal injection in vivo.
Specifications
Specifications
Chemical Name or Material | 2-Amino-5,8-dihydro-5-[3-methoxy-4-(2-propen-1-yloxy)phenyl]pyrido[2,3-d]pyrimidine-4,7(3H,6H)-dione |
CAS | 878437-15-1 |
Quantity | 50 mg |
Molecular Formula | C17H18N4O4 |
Formula Weight | 342.35 |
Purity | 98% |
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