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PAAF1 Mouse anti-Human, Clone: OTI1F11, liquid, TrueMAB™
SDP

Catalog No. 501677006
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100 μL
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Catalog No. Quantity
50-167-7006 100 μL
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Catalog No. 50-167-7006 Supplier OriGene Supplier No. TA507207
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Description

Mouse Monoclonal Antibody

PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.

Specifications

Antigen PAAF1
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone OTI1F11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene PAAF1
Gene Accession No. Q9BRP4
Gene Alias PAAF, Rpn14, WDR71
Gene Symbols PAAF1
Host Species Mouse
Immunogen Full length human recombit protein of human PAAF1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80227
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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