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Invitrogen™ PAAF1 Polyclonal Antibody
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Catalog No. PIPA559008
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100 μL
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PIPA559008 100 μL
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Catalog No. PIPA559008 Supplier Invitrogen™ Supplier No. PA559008
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Rabbit Polyclonal Antibody

Immunogen sequence: GNIYQLDVRS PRAPVQVIHR SGAPVLSLLS VRDGFIASQG DGSCFIVQQD LDYVTELTGA DCDPVYKVAT WEKQIYTCCR DGLVRRYQLS DL Highest antigen sequence identity to the following orthologs: Mouse - 20%, Rat - 22%.

PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAAF1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PAAF1
Gene Accession No. Q9BRP4
Gene Alias PAAF; PAAF1; proteasomal ATPase associated factor 1; proteasomal ATPase-associated factor 1; Protein G-16; Rpn14; WD repeat domain 71; WD repeat-containing protein 71; WDR71
Gene Symbols PAAF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PAAF1. Recombinant protein control fragment (Product #RP-97489).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80227
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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