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Invitrogen™ Pab1p Monoclonal Antibody (1G1)

Catalog No. PIMA547389
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250 μL
500 μL
2.5 mL
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PIMA547389 500 μL
PIMA547292 2.5 mL
PIMA547390 250 μL
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Catalog No. PIMA547389 Supplier Invitrogen™ Supplier No. MA547389
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Description

Mouse Monoclonal Antibody

Pab1p Monoclonal Antibody for Western Blot, ICC/IF, IHC, IP

The Pab1p protein was discovered in Saccharomyces cerevisia since it is abundant and binds specifically to the polyA tails of mRNA molecules. The systematic name in the Saccharomyces genome database is YER165w. It has a role in polyA length control in combination with Nab2p and may also be involved in mRNA stability and transcription. Pab1p is found in both the cytoplasm and nuclei of yeast cells and has a deduced molecular weight of 64 kDa, but runs on typical SDS-PAGE gels at about 67kDa. The yeast Pab1p protein sequence includes four RNA recognition motifs followed by a single C-terminal polyA binding domain. The closest human homolog of the yeast protein is polyadenylate-binding protein cytoplasmic 1-like (PABPC1L) which has the same domain structure, although is not well conserved in amino acid sequence. There are seven human genes encoding polyA binding proteins, four of which produce proteins with the same domain structure as yeast Pab1p and human PABPC1L.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pab1p
Applications Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1G1
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Cell culture media with 5mM sodium azide
Gene PAB1
Gene Accession No. P04147
Gene Alias Poly(A) binding protein
Gene Symbols PAB1
Host Species Mouse
Immunogen Yeast polyA binding protein preparations.
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 856912
Target Species Yeast, Bacteria
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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