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Invitrogen™ Pab1p Monoclonal Antibody (1G1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA547389

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Catalog No. PIMA547389


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Description

Description

Pab1p Monoclonal Antibody for Western Blot, ICC/IF, IHC, IP

The Pab1p protein was discovered in Saccharomyces cerevisia since it is abundant and binds specifically to the polyA tails of mRNA molecules. The systematic name in the Saccharomyces genome database is YER165w. It has a role in polyA length control in combination with Nab2p and may also be involved in mRNA stability and transcription. Pab1p is found in both the cytoplasm and nuclei of yeast cells and has a deduced molecular weight of 64 kDa, but runs on typical SDS-PAGE gels at about 67kDa. The yeast Pab1p protein sequence includes four RNA recognition motifs followed by a single C-terminal polyA binding domain. The closest human homolog of the yeast protein is polyadenylate-binding protein cytoplasmic 1-like (PABPC1L) which has the same domain structure, although is not well conserved in amino acid sequence. There are seven human genes encoding polyA binding proteins, four of which produce proteins with the same domain structure as yeast Pab1p and human PABPC1L.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Pab1p
Monoclonal
Conc. Not Determined
Cell culture media with 5mM sodium azide
P04147
PAB1
Yeast polyA binding protein preparations.
RUO
856912
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
1G1
Unconjugated
PAB1
Poly(A) binding protein
Mouse
500 μL
Primary
Yeast, Bacteria
Antibody
IgG2a
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