Invitrogen™ PABP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529883

Catalog No. PIPA529883

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, A549, H1299, Neuro2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2. Predicted reactivity: Mouse (99%), Rat (98%), Xenopus laevis (91%), Chicken (95%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4), and PABP3 (PABPC3). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.

Specifications

• Antigen: PABP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PABPC1
• Gene Alias: Cytoplasmic poly(A)-binding protein 1-A; ePAB; hypothetical protein; PAB1; pabp; PABP 1; Pabp1; PABP-1; PABP-1A; PABP-1-A; PABP-A; Pabpc1; pabpc1.L; pabpc1.S; pabpc1a; pabpc1-a; pabpc1a protein; pabpc1-b; pabpc2; PabpI; PABPL1; poly A binding protein 1; poly A binding protein, cytoplasmic 1 a; poly(A) binding protein cytoplasmic 1; poly(A) binding protein, cytoplasmic 1; poly(A) binding protein, cytoplasmic 1 L homeolog; poly(A) binding protein, cytoplasmic 1 S homeolog; poly(A) binding protein, cytoplasmic 1a; poly(A) binding protein, cytoplasmic 2; poly(A)-binding protein 1; poly(A)-binding protein 1A; poly(A)-binding protein 1-A; polyadenylate-binding protein 1; Polyadenylate-binding protein 1A; Polyadenylate-binding protein 1-A; polyadenylate-binding protein 1A; poly(A) binding protein, cytoplasmic 1a; wu:fb16a02; wu:fi19b08; wu:fj12d09; wu:fj61f06; XELAEV_18033915mg; xPABP1-A; zgc:109879
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171350, 18458, 26986
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Western Blot
• Concentration: 0.79 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P11940, P29341, Q9EPH8
• Gene Symbols: PABPC1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 356 and 630 of Human PABP.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov