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Invitrogen™ MZB1 Polyclonal Antibody
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Catalog No. PIPA521794
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100 μL
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PIPA521794 100 μL
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Catalog No. PIPA521794 Supplier Invitrogen™ Supplier No. PA521794
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Molt-4, Raji. Predicted reactivity: Rhesus Monkey (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MZB1
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.48 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene MZB1
Gene Accession No. Q8WU39, Q9D8I1
Gene Alias caspase-2 binding protein; HSPC190; marginal zone B and B1 cell specific protein; marginal zone B and B1 cell-specific protein; marginal zone B- and B1-cell-specific protein; MEDA7; MEDA-7; Mesenteric estrogen-dependent adipose 7; mesenteric oestrogen-dependent adipose gene- 7; MGC29506; MZB1; PACAP; pERp1; plasma cell-induced ER protein 1; plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; proapoptotic caspase adapter protein; proapoptotic caspase adaptor protein
Gene Symbols MZB1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PACAP. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51237, 69816
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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