Invitrogen™ PACRG Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566834

Catalog No. PIPA566834

Description

Immunogen sequence: AFKERPTKPTA FRKFYERGDF PIALEHDSKG NKIAWKVEIE KLDYHHYLPL F Highest antigen sequence identity to the following orthologs - mouse 94%, rat 29%.

PACRG is a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death.

Specifications

• Antigen: PACRG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PACRG
• Gene Alias: 1700008H23Rik; FLJ32724; GLUP; HAK005771; Hypertension-related protein 1-like protein; molecular chaperone/chaperonin-binding protein; PACRG; PARK2 coregulated; PARK2 co-regulated; PARK2 coregulated gene protein; PARK2CRG; parkin coregulated; parkin coregulated gene protein; parkin co-regulated gene protein; Parkin coregulated gene protein homolog; RGD1561027; RP3-495O10.2; Unknown (protein for MGC:134579); zgc:101786
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 135138
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96M98
• Gene Symbols: PACRG
• Immunogen: Recombinant Human PACRG. Recombinant protein control fragment (Product #RP-107490).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG