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PACRGRabbit anti-Chicken, Human, Mouse, Polyclonal, Rockland™

Rabbit Polyclonal Antibody
Supplier: Rockland Immunochemicals 600401474

Description
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity purified antibody is directed against human PACRG protein. A BLAST analysis was used to suggest reactivity with this protein from human, mouse and chicken based on 100% homology for the immunogen sequence. Cross reactivity with PACRG protein from zebrafish and rat may occur as this sequence only varies by one amino acid residue (94% homology). Expect reactivity with both splice variants of this protein. Cross reactivity with PACRG homologues from other sources has not been determined.
PACRG is a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death.Specifications
PACRG | |
Polyclonal | |
Unconjugated | |
PACRG | |
1700008H23Rik; BOS_10014; FLJ32724; GLUP; HAK005771; Hypertension-related protein 1-like protein; LOC100342049; Molecular chaperone/chaperonin-binding protein; PACRG; PARK2 coregulated; PARK2 co-regulated; PARK2 coregulated gene protein; PARK2CRG; parkin coregulated; Parkin coregulated gene protein; parkin co-regulated gene protein; Parkin coregulated gene protein homolog; RGD1561027; RP3-495O10.2; zgc:101786 | |
Rabbit | |
RUO | |
135138, 421576, 69310 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunoprecipitation, Western Blot | |
1.6 mg/mL | |
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2 | |
Q96M98, Q9DAK2 | |
PACRG | |
100 μg | |
Primary | |
Chicken, Human, Mouse | |
Antibody |
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