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Invitrogen™ PACS1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA523291
Description
PACS1 Polyclonal Antibody for Western Blot
PACS-1 (CRA_a) is a 963 amino acid rich regulatory protein involved in protein trafficking and belongs to the PACS family. A coat protein involved in controlling the correct subcellular localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs, PACS-1 is also known to be involved in HIV-1 Nef-mediated removal of MHC-I from the cell surface to the TGN, thus enabling HIV-1 to escape immune surveillance. PACS-1 also controls the endosome to Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin coated membrane pits. Usually seen in golgi apparatus, trans-Golgi network and localized in the paranuclear region, it is ubiquitously expressed in most of the tissues.
Specifications
PACS1 | |
Polyclonal | |
Unconjugated | |
PACS1 | |
AI325977; cytosolic sorting protein PACS-1; KIAA1175; LOW QUALITY PROTEIN: phosphofurin acidic cluster sorting protein 1; phosphofurin acidic cluster sorting protein 1; MRD17; PACS1; PACS-1; Phosphofurin acidic cluster sorting protein 1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
100052235, 107975, 483716, 514313, 55690 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 0.05% BSA and 0.05% sodium azide | |
Q6VY07, Q8K212 | |
PACS1 | |
A portion of amino acids 300-350 of human PACS-1. | |
100 μg | |
Primary | |
Human, Mouse, Canine, Monkey, Bovine, Horse, Marsupial | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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