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Invitrogen™ PACS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA523291

Catalog No. PIPA523291


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Description

Description

PACS1 Polyclonal Antibody for Western Blot

PACS-1 (CRA_a) is a 963 amino acid rich regulatory protein involved in protein trafficking and belongs to the PACS family. A coat protein involved in controlling the correct subcellular localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs, PACS-1 is also known to be involved in HIV-1 Nef-mediated removal of MHC-I from the cell surface to the TGN, thus enabling HIV-1 to escape immune surveillance. PACS-1 also controls the endosome to Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin coated membrane pits. Usually seen in golgi apparatus, trans-Golgi network and localized in the paranuclear region, it is ubiquitously expressed in most of the tissues.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PACS1
Polyclonal
Unconjugated
PACS1
AI325977; cytosolic sorting protein PACS-1; KIAA1175; LOW QUALITY PROTEIN: phosphofurin acidic cluster sorting protein 1; phosphofurin acidic cluster sorting protein 1; MRD17; PACS1; PACS-1; Phosphofurin acidic cluster sorting protein 1
Rabbit
Antigen Affinity Chromatography
RUO
100052235, 107975, 483716, 514313, 55690
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q6VY07, Q8K212
PACS1
A portion of amino acids 300-350 of human PACS-1.
100 μg
Primary
Human, Mouse, Canine, Monkey, Bovine, Horse, Marsupial
Antibody
IgG
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