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PACSIN2 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA596804
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100 μL
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PIPA596804 100 μL
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Catalog No. PIPA596804 Supplier Thermo Scientific Supplier No. PA596804

Description

Rabbit Polyclonal Antibody

Immunogen sequence: RLRFFREVLL EVQKHLDLSN VAGYKAIYHD LEQSIRAADA VEDLRWFRAN HGPGMAMNWP QFEEWSADLN RTLSRREKKK ATDGVTLTGI NQTGDQSLPS KPSSTLNVPS NPAQSAQSQS SYNPFEDEDD TGSTVSEKDD TKAKNVSSYE KTQSYPTDWS DDESNNPFSS T; Positive Samples: BT-474, HepG2, Mouse lung, Mouse heart; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle membrane, Early endosome, Membrane, Peripheral membrane protein, Recycling endosome membrane, caveola, cytoskeleton, ruffle membrane

PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PACSIN2
Applications Western Blot
Classification Polyclonal
Concentration 0.79 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene PACSIN2
Gene Accession No. Q9UNF0, Q9WVE8
Gene Alias AI197433, cytoplasmic phosphoprotein PACSIN2, Pacsin2, pacsin2.S, protein kinase C and casein kinase substrate in neurons 2, protein kinase C and casein kinase substrate in neurons 2 protein, protein kinase C and casein kinase substrate in neurons 2 S homeolog, protein kinase C and casein kinase substrate in neurons protein 2, RP3-437M21.1, SdpII, SdpIIsyndapin II, synaptic dynamin-associated protein II, syndapin 2, Syndapin II, syndapin2, syndapin-2, Syndapin-II, XELAEV_18019736mg, x-PACSIN2
Gene Symbols PACSIN2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PACSIN2 (NP_0091602)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11252, 23970
Target Species Human, Mouse
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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