PADI2 Mouse anti-Human, Mouse, Rat, Clone: 2D8C12, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-6815	Proteintech Group Inc 663861IG150UL	150 μL

Description

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Specifications

• Antigen: PADI2
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: KIAA0994, PAD H19, PAD2, PADI2, PADI2 protein, PDI 2, PDI2, Peptidylarginine deiminase II
• Gene Symbols: Padi2
• Isotype: IgG2b
• Purification Method: Protein A
• Product Type: Antibody

• Clone: 2D8C12
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P20717, Q08642, Q9Y2J8
• Gene ID (Entrez): 11240, 18600, 29511
• Immunogen: PADI2 Fusion Protein Ag17612
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PADI2