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Invitrogen™ PADI2 Polyclonal Antibody
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Catalog No. PIPA5106273
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PIPA5106273 100 μL
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Catalog No. PIPA5106273 Supplier Invitrogen™ Supplier No. PA5106273
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PADI2.

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PADI2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PADI2
Gene Accession No. P20717, Q08642, Q9Y2J8
Gene Alias KIAA0994; mKIAA0994; PAD type II; Pad2; PAD-H19; PADI2; Pdi; PDI2; peptidyl arginine deiminase 2; peptidyl arginine deiminase, type 2; peptidyl arginine deiminase, type II; peptidyl arginine deiminase, type II; PAD type II; peptidylarginine deiminase II; Protein-arginine deiminase type II; protein-arginine deiminase type-2; RP1-37C10.6
Gene Symbols PADI2
Host Species Rabbit
Immunogen A synthesized peptide derived from human PADI2(Accession Q9Y2J8), corresponding to amino acid residues S495-Q545.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11240, 18600, 29511
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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