PADI4 Mouse anti-Human, Clone: OTI5B7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF504897

Catalog No. 50-166-3233

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at ′Arg-8′ and/or ′Arg-17′ and histone H4 at ′Arg-3′, which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at ′Arg-2142′, which favors its interaction with NCOA2/GRIP1.

Specifications

• Antigen: PADI4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: PADI4
• Gene Alias: PAD, PAD4, PADI5, PDI4, PDI5
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23569
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot
• Clone: OTI5B7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9UM07
• Gene Symbols: PADI4
• Immunogen: Human recombit protein fragment corresponding to amino acids 299-588 of human PADI4 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a