Invitrogen™ PADI4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534702

Catalog No. PIPA534702

Description

Recommended positive controls: PAD4-transfected 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.

Specifications

• Antigen: PADI4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Padi4
• Gene Alias: HL-60 PAD; PAD; PAD type IV; PAD4; Padi4; PADI5; PADI-H protein; PAD-R4; Pdi4; PDI5; peptidyl arginine deiminase 4; peptidyl arginine deiminase, type 4; peptidyl arginine deiminase, type IV; peptidyl arginine deiminase, type V; peptidylarginine deiminase IV; Peptidylarginine deiminase type alpha; protein-arginine deiminase type IV; Protein-arginine deiminase type-4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23569
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9UM07
• Gene Symbols: Padi4
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PAD4. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov