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Invitrogen™ PADI4 Polyclonal Antibody
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Catalog No. PIPA5110070
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100 μL
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PIPA5110070 100 μL
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Catalog No. PIPA5110070 Supplier Invitrogen™ Supplier No. PA5110070
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Rabbit Polyclonal Antibody

Immunogen sequence: VFRVAPWIMT PNTQPPQEVY ACSIFENEDF LKSVTTLAMK AKCKLTICPE EENMDDQWMQ DEMEIGYIQA PHKTLPVVFD SPRNRGLKEF PIKRVMGPDF GYVTRGPQTG GISGLDSFGN LEVSPPVTVR GKEYPLGRIL FGDSCYPSND SRQMHQALQD FLSAQQVQAP VKLYSDWLSV GHVDEFLSFV PAPDRKGFRL LLASPRSCYK LFQEQQNEGH GEALLFEGIK KKKQQKIKNI LSNKTLREHN SFVERCIDWN RELLKRELGL AESDIIDIPQ LFKLKEFSKA EAFFPNMVNM LVLGKHLGIP KPFGPVINGR CCLEEKVCSL LEPLGLQCTF INDFFTYHIR HGEVHCGTNV RRKPFSFKWW NMVP.

Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PADI4
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.71 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene Padi4
Gene Accession No. O88807, Q9UM07, Q9Z183
Gene Alias HL-60 PAD; PAD; PAD type IV; PAD4; Padi4; PADI5; PADI-H protein; PAD-R4; Pdi4; PDI5; peptidyl arginine deiminase 4; peptidyl arginine deiminase, type 4; peptidyl arginine deiminase, type IV; peptidyl arginine deiminase, type V; peptidylarginine deiminase IV; Peptidylarginine deiminase type alpha; protein-arginine deiminase type IV; Protein-arginine deiminase type-4
Gene Symbols Padi4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 290-663 of human PADI4 (NP_0365192).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18602, 23569, 29512
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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