Invitrogen™ PAICS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531161

Catalog No. PIPA531161

Description

Recommended positive controls: Jurkat, Raji, K562, THP-1, HL-60, NCI-H929. Predicted reactivity: Mouse (94%), Rat (95%), Zebrafish (82%), Xenopus laevis (86%), Chicken (90%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PAICS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAICS
• Gene Alias: 2610511I09Rik; ADE2; ADE2H1; AIR carboxylase; Airc; Multifunctional protein ADE2; multifunctional protein ADE2H1; Paics; PAIS; Phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole succinocarboxamide synthetase; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase; phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazolesuccinocarboxamide synthase; Phosphoribosylaminoimidazole-succinocarboxamide synthase; SAICAR synthetase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10606
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P22234
• Gene Symbols: PAICS
• Immunogen: Recombinant fragment corresponding to a region within amino acids 179 and 425 of Human PAICS.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG