Invitrogen™ PAICS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550472

Catalog No. PA550472

Description

The antibody detects endogenous levels of total PAICS protein.

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PAICS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAICS
• Gene Alias: 2610511I09Rik; ADE2; ADE2H1; AIR carboxylase; Airc; Multifunctional protein ADE2; multifunctional protein ADE2H1; Paics; PAIS; Phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole succinocarboxamide synthetase; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase; phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazolesuccinocarboxamide synthase; Phosphoribosylaminoimidazole-succinocarboxamide synthase; SAICAR synthetase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10606
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.6 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P22234
• Gene Symbols: PAICS
• Immunogen: Fusion protein corresponding to residues near the N terminal of human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG