Invitrogen™ PAIP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563347

Catalog No. PIPA563347

Description

Immunogen sequence: KDPSRSSTSP SIINEDVIIN GHSHEDDNPF AEYM Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

Specifications

• Antigen: PAIP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAIP2
• Gene Alias: 2310050K10Rik; AU045972; HSPC218; MGC72018; PABC1-interacting protein 2; Pabp-interacting protein 2; PAIP2; PAIP-2; PAIP2A; poly(A) binding protein interacting protein 2; poly(A)-binding protein-interacting protein 2; polyA-binding protein-interacting protein 2; polyadenylate-binding protein interacting protein 2; polyadenylate-binding protein-interacting protein 2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51247
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BPZ3
• Gene Symbols: PAIP2
• Immunogen: Recombinant protein corresponding to Human PAIP2. Recombinant protein control fragment (Product #RP-103268).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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