Invitrogen™ PAK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534696

Catalog No. PIPA534696

Description

Recommended positive controls: A431, HeLa, BCL-1, PC-12, SH-SY5Y. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (81%), Xenopus laevis (85%), Chicken (95%), Bovine (99%). IHC notes, Requires antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PAK1 is a serine/threonine kinase that is a target for restenosis, cancer, and immunosuppression treatment. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.

Specifications

• Antigen: PAK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pak1
• Gene Alias: activated protein kinase alpha; ADRB2; adriamycin resistance-associated; alpha pak; alpha-PAK; ARA; AW045634; Beta-PAK; bPAK; CDC42/RAC effector kinase PAK-A; C-t-PAK2; EC 2.7.11.1; gamma-PAK; kinase PAK1; MGC130000; MGC130001; MRX30; MRX47; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 1; p21 (CDKN1A)-activated kinase 2; p21 (CDKN1A)-activated kinase 3; p21 (RAC1) activated kinase 1; p21 (RAC1) activated kinase 2; p21 (RAC1) activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 3; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21-activated kinase 1; p21-activated kinase 2; p21-activated kinase 3; p27; p34; p58; p65-PAK; p68-PAK; PAK 1; PAK1; PAK-1; PAK1B; PAK2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK3beta; PAK65; Paka; PAKalpha; PAKgamma; protein kinase MUK2; S6/H4 kinase; serine/threonine-protein kinase PAK 1; Serine/threonine-protein kinase PAK 2; serine/threonine-protein kinase PAK 3; STE20 homolog, yeast
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18479, 29431, 5058
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.48 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O88643, P35465, Q13153
• Gene Symbols: Pak1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 151 and 544 of PAK1 (Uniprot ID#Q13153).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov