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Invitrogen™ PAK1IP1 Polyclonal Antibody
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Catalog No. PIPA5100854
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100 μL
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PIPA5100854 100 μL
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Catalog No. PIPA5100854 Supplier Invitrogen™ Supplier No. PA5100854
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PAK1IP1.

Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAK1IP1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PAK1IP1
Gene Accession No. Q9DCE5, Q9NWT1
Gene Alias 5830431I15Rik; 5930415H02Rik; AA419825; AI314040; AW556169; bA421M1.5; Gdpd1; glycerophosphodiester phosphodiesterase domain containing 1; hPIP1; MAK11; p21-activated protein kinase-interacting protein 1; PAK/PLC-interacting protein 1; PAK1 interacting protein 1; PAK1-interacting protein 1; PAK1IP1; PIP1; putative PAK inhibitor Skb15; RP11-421M1.5; WD repeat-containing protein 84; WDR84
Gene Symbols PAK1IP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human PAK1IP1(Accession Q9NWT1), corresponding to amino acid residues E325-M375.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55003, 68083
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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