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Invitrogen™ PAK1IP1 Polyclonal Antibody
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Catalog No. PIPA583124
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100 μL
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PIPA583124 100 μL
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Catalog No. PIPA583124 Supplier Invitrogen™ Supplier No. PA583124
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Rabbit Polyclonal Antibody

Immunogen sequence: GTITNEKRIS SVKFLSESVL AVAGDEEVIR FFDCDSLVCL CEFKAHENRV KDMISFEIPE HHVIVSASSD GFIKMWK Highest antigen sequence indentity to the following orthologs: Mouse - 82%, Rat - 82%.

Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAK1IP1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PAK1IP1
Gene Accession No. Q9NWT1
Gene Alias 5830431I15Rik; 5930415H02Rik; AA419825; AI314040; AW556169; bA421M1.5; Gdpd1; glycerophosphodiester phosphodiesterase domain containing 1; hPIP1; MAK11; p21-activated protein kinase-interacting protein 1; PAK/PLC-interacting protein 1; PAK1 interacting protein 1; PAK1-interacting protein 1; PAK1IP1; PIP1; putative PAK inhibitor Skb15; RP11-421M1.5; WD repeat-containing protein 84; WDR84
Gene Symbols PAK1IP1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PAK1IP1. Recombinant protein control fragment (Product #RP-108332).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55003
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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