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Invitrogen™ PAK2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5121863
This item is not returnable.
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Description
PAK2 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)
PAK2 (serine/threonine-protein kinase PAK2) is a serine/threonine kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, or proliferation. It acts as a downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformation change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities.
Specifications
PAK2 | |
Polyclonal | |
Unconjugated | |
Pak2 | |
5330420P17Rik; A130002K10Rik; AI836325; Alpha-PAK; Beta-PAK; C-t-PAK2; D16Ertd269e; gamma pak; gamma-PAK; mKIAA4182; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 2; p21 (RAC1) activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; p27; p34; p58; p65-PAK; PAK alpha; PAK beta; PAK gamma; PAK1; PAK-1; Pak2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK65; PAKgamma; S6/H4 kinase; serine/threonine-protein kinase PAK 2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
5062 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
500 μg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
Q13177 | |
Pak2 | |
Recombinant protein p21 Protein Activated Kinase 2. The antigen corresponds to amino acid range 177-419 of the target protein. | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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