Invitrogen™ Pan B Cells Monoclonal Antibody (CVS36)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA528501

Catalog No. PIMA528501

Description

This antibody recognizes equine Ig light chains. Characterization studies demonstrated that clone CVS36 bound 100% of CD5-ve peripheral blood lymphocytes and recognized all equine B-cells.

Pan B Cells antibody specific anti equine reagents have yet to be fully characterized for the typically recognized B-cell makers such as CD19, CD20, CD21, CD22 and CD79. While testing has demonstrated the cross reactivity of some monoclonal B-cell markers raised against other species with equine B cells, such as the Mouse anti Human CD79a antibody, (clone HM57), an overview of which may be found in the report of the second equine leucocyte antigen workshop. Pan B Cells antibody is directed against equine Ig light chains. Characterization studies demonstrated that clone CVS36 bound 100% of CD5-ve peripheral blood lymphocytes and recognized all equine B-cells (Lunn et al. 1998) As the antigen recognized by clone CVS36 appears to be present on the surface of all equine B-cells it is therefore is a reagent that can be used as a pan B-cell marker for domestic horses.

Specifications

• Antigen: Pan B Cells
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Immunogen: Purified Equine Ig.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry
• Clone: CVS36
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Horse
• Product Type: Antibody
• Isotype: IgG1