Invitrogen™ Cytokeratin 1 Antibody Cocktail

Catalog No.	Quantity
PIMA549309	100 μg

Catalog No. PIMA549309 Supplier Invitrogen™ Supplier No. MA549309

Description

Antibody Cocktail

Adding 1 mL of PBS buffer will yield a concentration of 100 μg/mL. Positive Control - WB: human NCL-H460 whole cellhuman Hela whole cellhuman A431 whole cell. IHC: Human Placenta tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Specifications

• Antigen: Cytokeratin 1
• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Classification: Cocktail
• Clone: C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2
• Concentration: 100 μg/mL
• Conjugate: Unconjugated
• Formulation: 1.2% sodium acetate with 2mg BSA and 0.01mg sodium azide
• Gene: KRT1
• Gene Accession No.: P04264, Q6IMF3
• Gene Alias: 67 kDa cytokeratin; CK1; CK-1; cytokeratin 1; cytokeratin-1; EHK; EHK1; epidermolytic hyperkeratosis 1; epithelial keratin 1; Epithelial keratin-1; EPPK; Hair alpha protein; K1; Kb1; KER1; keratin 1; keratin 1 (epidermolytic hyperkeratosis); keratin 1, type II; keratin 86; keratin complex 2, basic, gene 1; keratin, type II cytoskeletal 1; Keratin-1; KRT1; krt1 {ECO:0000250; KRT1A; Krt-2.1; Krt2-1; Krt86; KRTA; NEPPK; type II keratin Kb1; type-II keratin Kb1; UniProtKB:P04264}
• Gene Symbols: KRT1
• Host Species: Mouse
• Immunogen: mixture of several monoclonal cytokeratin clones.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 300250, 3848
• Target Species: Human, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1, IgG2a