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Invitrogen™ pan T cells Monoclonal Antibody (OX-52)
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Catalog No. PIMA517530
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500 μg
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Catalog No. Quantity
PIMA517530 500 μg
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Catalog No. PIMA517530 Supplier Invitrogen™ Supplier No. MA517530
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Description

Mouse Monoclonal Antibody

MA5-17530 targets pan T cells in FACS, IHC (F), and IP applications and shows reactivity with Rat samples. The MA5-17530 immunogen is immunogen:PVG-RT1c thoracic duct lymphocytes and spleen cells.

Pan T cells, encompassing all T lymphocyte subsets, are integral to the adaptive immune system, originating from hematopoietic stem cells in the bone marrow and maturing in the thymus. These cells include helper T cells (CD4+), cytotoxic T cells (CD8+), regulatory T cells, and memory T cells, each playing distinct roles in immune defense. Pan T cells are characterized by the expression of the T-cell receptor (TCR) complex, which enables antigen recognition and response. The diversity within pan T cells allows for a broad range of functions, from direct cytotoxic effects on infected or malignant cells to regulatory roles in maintaining immune tolerance and memory responses for long-term immunity. These cells also interact with other immune components, enhancing or modulating responses to pathogens and tumors. Pan T cells are pivotal in cancer immunotherapy, where targeting specific T cell subsets can enhance anti-tumor immunity and overcome resistance mechanisms.
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Specifications

Antigen pan T cells
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Classification Monoclonal
Clone OX-52
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Host Species Mouse
Immunogen Immunogen:PVG-RT1c thoracic duct lymphocytes and spleen cells.
Purification Method Protein G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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