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Invitrogen™ Pannexin 1 Recombinant Rabbit Monoclonal Antibody (7E8T3)
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Catalog No. PIMA535664
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100 μL
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PIMA535664 100 μL
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Catalog No. PIMA535664 Supplier Invitrogen™ Supplier No. MA535664
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Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: DLSLYNLFLE ENISEVKSYK CLKVLENIKS SGQGIDPMLL LTNLGMIKMD VVDGKTPMSA EMREEQGNQT AELQGMNIDS ETKANNGEKN ARQRLLDSSC.

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pannexin 1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 7E8T3
Concentration 0.21 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PANX1
Gene Accession No. P60570, Q96RD7, Q9JIP4
Gene Alias AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028
Gene Symbols PANX1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 327-426 of human Pannexin 1 (Q96RD7).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24145, 315435, 55991
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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