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Invitrogen™ Pannexin 1 Recombinant Rabbit Monoclonal Antibody (28G5)
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Catalog No. FEMA550140
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100 μL
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FEMA550140 100 μL
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Catalog No. FEMA550140 Supplier Invitrogen™ Supplier No. MA550140
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Description

Rabbit Recombinant Monoclonal Antibody

Pannexin 1 Recombinant Monoclonal Antibody for ELISA, Flow, ICC/IF, IHC (P)

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pannexin 1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Recombinant Monoclonal
Clone 28G5
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.4
Gene PANX1
Gene Accession No. Q96RD7
Gene Alias AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028
Gene Symbols PANX1
Host Species Rabbit
Immunogen A synthesized peptide derived from Human PANX1 (aa 366-426).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24145
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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