Invitrogen™ Pannexin 1 Recombinant Rabbit Monoclonal Antibody (28G5)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA550140

Catalog No. FEMA550140

Description

Pannexin 1 Recombinant Monoclonal Antibody for ICC/IF, IHC (P), Flow, ELISA

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

Specifications

• Antigen: Pannexin 1
• Classification: Recombinant Monoclonal
• Concentration: 0.21 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q96RD7
• Gene Symbols: PANX1
• Immunogen: A synthesized peptide derived from Human PANX1 (aa 366-426).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry
• Clone: 28G5
• Conjugate: Unconjugated
• Gene: PANX1
• Gene Alias: AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24145
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid