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PANX1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501728096 Shop All Proteintech Group Inc Products
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50-172-8096 150 μL
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Catalog No. 50-172-8096 Supplier Proteintech Group Inc Supplier No. 125951AP150UL
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Description

Rabbit Polyclonal Antibody

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

Specifications

Antigen PANX1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PANX1
Gene Accession No. Q96RD7
Gene Alias MRS1, pannexin 1, PANX1, PX1, UNQ2529
Gene Symbols PANX1
Host Species Rabbit
Immunogen PANX1 Fusion Protein Ag3174
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24145
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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