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PANX2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen PANX2
Concentration 0.6 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-5396
SDP
Encompass_Preferred
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Proteintech Group Inc
266041AP150UL
150 μL
Each of 1 for $518.60
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Description

Description

Product No. 26604-1-AP specifically recognizes the 70 kDa Panx2.

Gap junctions are channel-forming structures that allow direct metabolic and electrical communication between adjacent cells of almost all types in mammalian tissues. In the human body, they are absent only in adult skeletal muscle cells and some circulating blood cells. A gap junction is formed two hemichannels, one in each of the neighboring cells, composed of six subunits. In mice and humans, at least 20 connexin and 3 pannexin genes encode gap junction proteins. Connexins are only found in chordates, while pannexins are present in both chordate and invertebrate genomes. Pannexins, previously known as innexins, are predicted to have four transmembrane regions, two extracellular loops, one intracellular loop, and intracellular N- and C-termini. Both human and mouse genomes contain three pannexin-encoded genes. Pannexin 2 (Px2, PANX2) appears to be a brain specific gene, and is abundantly expressed in the central nervous system, as is pannexin 1. In many neuronal cell populations, including hippocampus, olfactory bulb, cortex, and cerebellum, pannexin 1 and pannexin 2 are co-expressed; in other brain regions such as white matter, only pannexin 1-positive cells are found.
Specifications

Specifications

PANX2
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
Human, Mouse
Q6IMP4, Q96RD6
406218, 56666
PANX2 Fusion Protein Ag24256
Primary
-20°C
PANX2
0.6 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
hPANX2, pannexin 2, PANX2, PX2
Panx2
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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