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Invitrogen™ PAOX Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA570001
Description
This target displays homology in the following species: Cow: 85%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 92%; Rabbit: 85%; Rat: 86%.
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380). [UniProt].
Specifications
PAOX | |
Polyclonal | |
Unconjugated | |
Paox | |
2410012F02Rik; AI118225; exo-N4-amino; PAO; Paox; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase; polyamine oxidase; polyamine oxidase (exo-N4-amino); polyamine oxidase (exo-N4-amino) isoform 1; putative GTP-binding protein; UNQ1923/PRO4398 | |
Rabbit | |
Affinity chromatography | |
RUO | |
293589 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
0 | |
Paox | |
synthetic peptide directed towards the middle region of rat PAOX. | |
100 μL | |
Primary | |
Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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