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Invitrogen™ PAOX Polyclonal Antibody
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Catalog No. PIPA5104000
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100 μL
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PIPA5104000 100 μL
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Catalog No. PIPA5104000 Supplier Invitrogen™ Supplier No. PA5104000
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PAOX.

Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAOX
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Paox
Gene Accession No. Q6QHF9, Q8C0L6
Gene Alias 2410012F02Rik; AI118225; exo-N4-amino; PAO; Paox; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase; polyamine oxidase; polyamine oxidase (exo-N4-amino); polyamine oxidase (exo-N4-amino) isoform 1; putative GTP-binding protein; UNQ1923/PRO4398
Gene Symbols Paox
Host Species Rabbit
Immunogen A synthesized peptide derived from human PAOX(Accession Q6QHF9), corresponding to amino acid residues A286-H336.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 196743, 212503, 293589
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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