PAPK/ALS2CR2 Rabbit anti-Human, Polyclonal, Bioss 

Rabbit Polyclonal Antibody

Manufacturer:  Bioss BS3928R

Catalog No. 50-198-5761

Description

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene.

Specifications

• Antigen: PAPK/ALS2CR2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: STRADB
• Format: Liquid
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 55437

• Gene Symbol: STRADB
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q9C0K7
• Gene Alias: AA792893; Als2cr2; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog; B830008M19; BOS_2002; CALS-21; D1Ucla2; ILP-interacting protein; ILP-interacting protein homolog; ILP-interacting protein ILPIPA; ILPIP; ILPIPA; MGC102916; Papk; polyploidy associated protein kinase; polyploidy associated protein kinase PAPK-A; Polyploidy-associated protein kinase; PRO1038; Pseudokinase ALS2CR2; RGD1559449; STE20-related kinase adapter protein beta; STE20-related kinase adaptor beta; STRAD beta; STRADB; Syradb
• Immunogen: KLH conjugated synthetic peptide derived from human ALS2CR2.
• Purification Method: Protein A
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human