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PAPOL A+B+G Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
SDP

Catalog No. 501989067
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50-198-9067 100 μL
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Catalog No. 50-198-9067 Supplier Bioss Supplier No. BS9435R
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Description

Rabbit Polyclonal Antibody

Polyadenylation of the 3-prime ends of eukaryotic mRNAs is a key event that takes place in the nucleus during maturation of mRNA. The reaction includes endoribonucleolytic cleavage of the pre-RNA at the poly(A) site that leads to synthesis of the poly(A) tail at the 3-prime end of the upstream cleavage product. The poly(A) polymerase (PAP) is required The adenosine addition reaction depends on poly(A) polymerase (PAP) activity. The testis express PAP-beta (TPAP) in the cytoplasm of spermatogenic cells. The adenosine addition function of PAP-beta plays a critical role in male germ cell production. PAP-beta-deficient transgenic mice display impaired expression of haploid-specific genes that are necessary for spermatogenesis. The intronless gene encoding human PAP-beta maps to chromosome 7p22.3.

Specifications

Antigen PAPOL A+B+G
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PAPOLA
Gene Accession No. P51003, Q61183, Q6PCL9, Q9BWT3, Q9NRJ5, Q9WVP6
Gene Symbols PAPOLA, PAPOLB, PAPOLG
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PAPOLA/PAPOLB/PAPOLG.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10914, 18789, 216578, 304300, 305586, 314417, 56522, 56903, 64895
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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