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PAPP A2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989449
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50-198-9449 100 μL
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Catalog No. 50-198-9449 Supplier Bioss Supplier No. BS9916R
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Description

Rabbit Polyclonal Antibody

PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.

Specifications

Antigen PAPP A2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PAPPA2
Gene Accession No. Q9BXP8
Gene Alias LOC680415; PAPPA2; PAPP-A2; pappalysin 2; Pappalysin-2; Pappe; PAPP-E; PLAC3; placenta-specific 3; pregnancy-associated plasma preproprotein-A2; Pregnancy-associated plasma protein A2; Pregnancy-associated plasma protein E1; pregnancy-associated plasma protein-E; RP4-774I24.1; similar to pappalysin 2 isoform 1
Gene Symbols PAPPA2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PAPP A2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60676
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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