Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. ABS0060102

Invitrogen™ PAPPA Monoclonal Antibody (PAPP A 1-1)
GREENER_CHOICE

Catalog No. ABS0060102
Change view
Click to view available options
Quantity:
400 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
ABS0060102 400 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. ABS0060102 Supplier Invitrogen™ Supplier No. ABS0060102
Only null left
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

ABS 006-01-02 detects native Pregnancy-associated plasma protein A (PAPP-A) from human samples. ABS 006-01-02 has been successfully used in Western blotting, Immunohistochemistry and ELISA procedures. By Western blot, only unreduced forms of PAPA-A can be detected. In sandwich ELISA with a polyclonal antibody in coat, ABS 006-01-02 only reacts poorly with PAPP-A in third trimester serum. The epitope of ABS 006-01-02 is different from BTE 004-09-02 and ABS 006-24-02. The epitope is located on the PAPP-A subunit of the heterotetramer. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAPPA
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone PAPP A 1-1
Concentration 1.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 15 mM sodium azide; pH 7.4
Gene PAPPA
Gene Accession No. Q13219
Gene Alias 8430414N03Rik; ASBABP2; aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; DIPLA1; IGFBP-4 ase; IGFBP-4ase; IGF-dependent IGFBP-4 protease; insulin-like growth factor-dependent IGF binding protein-4 protease; insulin-like growth factor-dependent IGF-binding protein 4 protease; PAG1; PAPA; PAPP A; PAPPA; PAPP-A; PAPPA1; Pappalysin; pappalysin 1; pappalysin-1; pregnacy-associated plasma protein A; pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1; RP11-45A16.1
Gene Symbols PAPPA
Host Species Mouse
Immunogen Purified human PAPP-A.
Purification Method Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5069
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1 κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.