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Invitrogen™ PAPPA Polyclonal Antibody
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Catalog No. PIPA581964
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100 μL
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PIPA581964 100 μL
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Catalog No. PIPA581964 Supplier Invitrogen™ Supplier No. PA581964
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SCLDHNSESI ILPMNVTVRD IPHWLNPTRV ERVVCTAGLK WYPHPALIHC VKGCEPFMGD NYCDAINNRA FCNYDGGDCC TSTVKTKKVT PFPMSCDLQG DCACRDPQAQ EHSRKDL Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 92%.

Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAPPA
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PAPPA
Gene Accession No. Q13219
Gene Alias 8430414N03Rik; ASBABP2; aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; DIPLA1; IGFBP-4 ase; IGFBP-4ase; IGF-dependent IGFBP-4 protease; insulin-like growth factor-dependent IGF binding protein-4 protease; insulin-like growth factor-dependent IGF-binding protein 4 protease; PAG1; PAPA; PAPP A; PAPPA; PAPP-A; PAPPA1; Pappalysin; pappalysin 1; pappalysin-1; pregnacy-associated plasma protein A; pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1; RP11-45A16.1
Gene Symbols PAPPA
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PAPPA. Recombinant protein control fragment (Product #RP-94773).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5069
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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